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Stem Cell Ruling Leaves Some Disability

Stem Cell Ruling Leaves Some Disability Research In Limbo

A court action earlier this week halting federal funding for research involving human embryonic stem cells is leaving some research into developmental disabilities up in the air. On Monday,...

Jonathan Shar - avatar Jonathan Shar Comments 04 Sep 2010 Hits:20 Reel

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Couple Accused Of Bilking $380,000 In Au

A California couple is accused of defrauding their school district and health insurer, all in what they say was an effort to secure the best services...

Jonathan Shar - avatar Jonathan Shar Comments 04 Sep 2010 Hits:17 Reel

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Jobless Rate 60 Percent Higher For Ameri

A first-of-its-kind look at disability employment released Wednesday indicates that just 1 in 5 people with disabilities are employed and they’re disproportionately working part-time. According to the report from...

Jonathan Shar - avatar Jonathan Shar Comments 04 Sep 2010 Hits:13 Reel

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An update on peptide drugs for voltage-gated calcium channels PDF Print E-mail
Written by Gao L   
Monday, 08 March 2010 06:47
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Voltage-gated calcium channels are one of the major ion channels distributed in the human central nervous system,
and mediate an influx of extracellular Ca(2+) in response to membrane depolarization. Calcium channels are of particular
interest in a broad range of cellular functions including cell proliferation and differentiation, gene expression,
neurite outgrowth, transmitter and hormone release, and brain plasticity. The dysfunction of calcium channels is
related to a variety of clinical disorders such as migraine, hemiplegia, and epilepsy. Therefore, calcium channels
have gained great pharmaceutical interest as a privileged target class for the treatment of a wide range of human
diseases. This review will examine the known marketed peptide drugs for calcium channels and address the development
of some important patented peptide molecules targeting calcium channels

 

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